Do you know what is gene mutation and what havoc it can create? A gene mutation is a permanent change in the DNA sequence that makes up a gene. Mutations range in size from a single DNA building block (DNA base) to a large segment of a chromosome. The changes can result in various disorders of incurable types.
Most recently British scientists have found that mutation is responsible for age-related macular degeneration. This is a serious kind of eye disease that affects the old people and can lead to permanent blindness. It involves damage to the delicate cells of the macula, a region at the center of the retina.
Wet AMD, which occurs when tiny new blood vessels grow between the retina and the back of the eye can be treated with modern drugs. Around 90 percent of patients diagnosed with AMD have the so-called dry version, for which no treatment is currently available.
Imagine, blind! A world of total darkness. And who is the culprit? Well variants of the the gene Serping1. And they are six in number.
Well this is an important finding If the mutation can be corrected somehow, vision loss can be avoided. Such is the belief of Sarah Ennis and Andrew Lotery of the University of Southampton.