Artificial lens coated with antibiotic may reduce post operative eye infection

Now there is a good news for cataract patients as new research presented at the British Pharmaceutical Conference (BPC) in Manchester reveals that artificial lens if coated with an antibiotic named hydrogel, shows significant reduction in the risk of post-operative eye infection "endophthalmitis ".

Infectious Endophthalmitis is a rare but serious inflammation of the tissues inside the eye that can lead to blindness. It is often caused by bacteria entering the eye during cataract surgery and binding to the IOL (Intraocular lens). Great efforts including eyedrops prior to surgery; injecting antibiotics into the eye after surgery etc are manufactured to reduce the infections that is caused due the bacteria.

But now for the first time this new eye hydrogel has been made to hold the antibiotic, gentamicin. This hydrogel, loaded with antibiotic will help, to protect the eye against infection during and immediately after surgery. And thus improving the method of cataract surgery and the materials from which the IOLs are manufactured.

The idea is that after placing the artificial lens in its place, the antibiotics which is loaded in the coating, will be gradually released, killing bacteria within the eye and preventing them from sticking to the IOL surface.

Researchers at the School of Pharmacy, Queen's University Belfast, are excited by a new type of hydrogel and hope that the concept of the hydrogel will show the same positive result in the pre-clinical and clinical trial as it was shown in laboratory-based research.



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