Nanoceria is a Good Vessel for Delivering Drugs Directly Into the Eye nanoceria是一个很好的船只运送毒品直接进入眼睛
Sudipta Seal at the University of Central Florida in Orlando was testing cerium oxide nanoparticles, or nanoceria, for use as a catalyst to remove grime from oven walls, when he realised they might have medical applications. sudipta密封在中佛罗里达大学在奥兰多被测试氧化铈纳米颗粒,或nanoceria ,使用作为一种催化剂,以消除污垢从炉墙,当他意识到他们可能有医疗应用。
Surprisingly, not only did nanoceria not irritate the eyes of rats and rabbits, in some cases they helped protect cells from light damage (New Scientist, 30 August 2003, p 16).奇怪的是,不但没有nanoceria不刺激眼睛大鼠和家兔,在某些情况下,他们帮助保护细胞的光损伤(新科学家, 2003年8月30日,磷16 ) 。 Hence Seal realised that nanoceria might make a good vessel for delivering drugs directly into the eye.因此,密封意识到nanoceria可能会使一个良好的船只运送毒品直接进入眼睛。
Glaucoma involves an abnormal build-up of fluid inside the eye.青光眼涉及一种不正常的累积流体内眼。 Existing eye-drop treatments contain chemicals that don't attach to transport proteins very effectively, so only a small amount gets through the cornea.现有滴眼液治疗含有化学物质,不重视运输蛋白非常有效,所以只是一个很小的数目获得通过角膜。 Now Seal and colleague Sanku Mallik have successfully combined nanoceria with a compound that blocks the hCAII enzyme, which is involved in producing fluid inside the eye (The Journal of Physical Chemistry B, DOI: 10.1021/jp067666l).现在,印章和同事sanku mallik已成功地结合nanoceria与复合拦截hcaii酶,这是涉及在生产流体内眼(日刊物理化学b ,土井: 10.1021/jp067666l ) 。
Source: NewScientist资料来源: newscientist
Filed under提起下 Eye Treatment眼科治疗 , , Glaucoma青光眼 | |
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